Kenneth C Anderson Selected Research

pomalidomide

1/2022	Isatuximab plus pomalidomide and low-dose dexamethasone versus pomalidomide and low-dose dexamethasone in patients with relapsed and refractory multiple myeloma (ICARIA-MM): follow-up analysis of a randomised, phase 3 study.
11/2021	Indatuximab ravtansine plus dexamethasone with lenalidomide or pomalidomide in relapsed or refractory multiple myeloma: a multicentre, phase 1/2a study.
1/2021	Immunomodulatory drugs activate NK cells via both Zap-70 and cereblon-dependent pathways.
1/2020	The immunomodulatory drugs lenalidomide and pomalidomide enhance the potency of AMG 701 in multiple myeloma preclinical models.
12/2019	Isatuximab plus pomalidomide and low-dose dexamethasone versus pomalidomide and low-dose dexamethasone in patients with relapsed and refractory multiple myeloma (ICARIA-MM): a randomised, multicentre, open-label, phase 3 study.
1/2019	A genome-scale CRISPR-Cas9 screening in myeloma cells identifies regulators of immunomodulatory drug sensitivity.
5/2018	Isatuximab plus pomalidomide/dexamethasone versus pomalidomide/dexamethasone in relapsed/refractory multiple myeloma: ICARIA Phase III study design.
1/2018	Investigational agents in immunotherapy: a new horizon for the treatment of multiple myeloma.
5/2015	Multiple myeloma: new uses for available agents, excitement for the future.
1/2015	Current treatment landscape for relapsed and/or refractory multiple myeloma.

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Kenneth C Anderson Research Topics

Disease

512	Multiple Myeloma 06/2022 - 01/2002
256	Neoplasms (Cancer) 01/2022 - 01/2002
33	Waldenstrom Macroglobulinemia (Macroglobulinemia) 11/2021 - 04/2003
30	Hematologic Neoplasms (Hematological Malignancy) 01/2022 - 04/2002
18	Disease Progression 01/2022 - 06/2005
16	Lymphoma (Lymphomas) 01/2022 - 04/2003
15	Thrombocytopenia (Thrombopenia) 01/2022 - 05/2002
11	Neutropenia 01/2022 - 12/2004
10	Plasmacytoma 01/2017 - 09/2002
10	Peripheral Nervous System Diseases (PNS Diseases) 12/2015 - 07/2006
9	Residual Neoplasm 10/2021 - 01/2011
9	Anemia 11/2018 - 01/2009
8	Fatigue 01/2022 - 07/2006
8	Leukemia 10/2019 - 04/2002
8	Bone Diseases (Bone Disease) 01/2019 - 01/2002
7	Carcinogenesis 01/2019 - 10/2007
6	Chromosomal Instability (Chromosome Stability) 09/2015 - 07/2002
5	Breast Neoplasms (Breast Cancer) 08/2021 - 02/2011
5	Severe Combined Immunodeficiency (Bare Lymphocyte Syndrome) 11/2011 - 07/2005
4	Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse) 11/2021 - 07/2006
4	Mantle-Cell Lymphoma (Lymphoma, Mantle Cell) 01/2019 - 02/2005
4	Paraproteinemias (Monoclonal Gammopathy) 03/2016 - 09/2008

Drug/Important Bio-Agent (IBA)

147	Bortezomib (Velcade)FDA Link 01/2022 - 05/2002
75	Proteasome InhibitorsIBA 04/2022 - 05/2002
68	Dexamethasone (Maxidex)FDA LinkGeneric 01/2022 - 02/2002
66	Lenalidomide (CC 5013)FDA Link 01/2022 - 11/2002
48	Pharmaceutical PreparationsIBA 10/2021 - 01/2002
40	Thalidomide (Thalomid)FDA Link 01/2021 - 04/2002
39	Proteins (Proteins, Gene)FDA Link 01/2022 - 03/2002
36	Proteasome Endopeptidase Complex (Proteasome)IBA 01/2022 - 10/2002
30	Biological ProductsIBA 10/2021 - 01/2002
28	Interleukin-6 (Interleukin 6)IBA 10/2021 - 05/2002
27	Immunomodulating AgentsIBA 11/2021 - 05/2002
25	Monoclonal AntibodiesIBA 12/2021 - 04/2003
24	CytokinesIBA 09/2011 - 05/2002
23	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2016 - 02/2002
22	AntigensIBA 12/2021 - 04/2003
22	Melphalan (Alkeran)FDA LinkGeneric 01/2018 - 07/2002
18	NF-kappa B (NF-kB)IBA 07/2013 - 05/2002
17	bis(3- bis(4- chlorophenyl)methyl- 4- dimethylaminophenyl)amineIBA 12/2021 - 05/2005
15	pomalidomideIBA 01/2022 - 09/2006
14	DNA (Deoxyribonucleic Acid)IBA 01/2020 - 03/2003
12	Histone Deacetylase InhibitorsIBA 01/2018 - 04/2003
11	Biomarkers (Surrogate Marker)IBA 10/2021 - 10/2007
11	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2021 - 03/2002
11	Peptides (Polypeptides)IBA 01/2021 - 06/2003
10	Immunoconjugates (Immunoconjugate)IBA 12/2021 - 07/2004
10	MicroRNAs (MicroRNA)IBA 01/2020 - 04/2009
10	EnzymesIBA 01/2018 - 10/2003
10	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 11/2014 - 01/2003
9	Immunoglobulins (Immunoglobulin)IBA 02/2022 - 03/2002
9	UbiquitinIBA 01/2022 - 08/2006
9	B-Cell Maturation AntigenIBA 12/2021 - 07/2006
9	Histone Deacetylases (Histone Deacetylase)IBA 01/2020 - 10/2003
9	Phosphotransferases (Kinase)IBA 12/2017 - 03/2004
9	perifosineIBA 08/2012 - 05/2006
8	elotuzumabIBA 12/2021 - 08/2008
8	LigandsIBA 10/2021 - 03/2002
8	Vorinostat FDA Link 01/2016 - 04/2003
8	Heat-Shock Proteins (Heat-Shock Protein)IBA 01/2015 - 10/2002
8	tanespimycin (17AAG)IBA 12/2011 - 02/2006
8	Insulin-Like Growth Factor I (IGF-1)IBA 01/2009 - 08/2002
8	Telomerase (Telomerase Reverse Transcriptase)IBA 08/2008 - 04/2002
7	daratumumabIBA 12/2021 - 02/2011
7	Immunoglobulin M (IgM)IBA 11/2021 - 04/2003
7	Alkylating AgentsIBA 01/2021 - 08/2006
7	carfilzomibIBA 10/2020 - 07/2013
7	Prednisone (Sone)FDA LinkGeneric 01/2018 - 08/2005
7	Immunoglobulin G (IgG)IBA 07/2014 - 07/2005
7	Rituximab (Mabthera)FDA Link 09/2010 - 01/2005
7	Antineoplastic Agents (Antineoplastics)IBA 05/2010 - 09/2002
6	Histones (Histone)IBA 10/2021 - 05/2009
6	Messenger RNA (mRNA)IBA 01/2021 - 04/2002
6	AntibodiesIBA 11/2019 - 03/2002
6	marizomibIBA 09/2016 - 11/2005
6	PanobinostatIBA 10/2013 - 11/2011
6	CaspasesIBA 06/2013 - 11/2003
6	GlucocorticoidsIBA 07/2012 - 01/2005
6	Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA 07/2009 - 04/2003
6	Cytotoxins (Cytolysins)IBA 04/2009 - 07/2004
6	Insulin-Like PeptidesIBA 01/2009 - 07/2002
6	InterleukinsIBA 01/2009 - 05/2004
5	isatuximabIBA 01/2022 - 08/2017
5	Complement System Proteins (Complement)IBA 01/2020 - 04/2003
5	ixazomibIBA 01/2018 - 08/2011
5	Zoledronic Acid (Zometa)FDA Link 03/2016 - 02/2009
5	Sirolimus (Rapamycin)FDA Link 11/2014 - 12/2004
5	Interleukin-6 Receptors (Interleukin 6 Receptor)IBA 12/2012 - 06/2005
5	enzastaurinIBA 07/2011 - 02/2007
5	Protein Kinase CIBA 02/2009 - 05/2004
4	Chimeric Antigen ReceptorsIBA 12/2021 - 11/2019
4	Transforming Growth Factor beta (TGF-beta)IBA 01/2020 - 01/2007
4	Transcription Factors (Transcription Factor)IBA 01/2019 - 06/2002
4	Caspase 3 (Caspase-3)IBA 08/2017 - 09/2005

Therapy/Procedure

201	Therapeutics 06/2022 - 01/2002
27	Drug Therapy (Chemotherapy) 01/2021 - 01/2002
22	Immunotherapy 01/2022 - 06/2003
21	Stem Cell Transplantation 01/2022 - 01/2002
11	Transplantation 01/2022 - 01/2002
4	Precision Medicine 12/2021 - 10/2015